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US FDA and ICH issued a series of guidance’s to assists the sponsor and applicants in the generic drug development.

The November month has around 11 new/revised guidance under GDUFA and ICH provisions. The links of the guidance’s are provided below for quick review and reference.

FDA:

1. Expanded Access to Investigational Drugs for Treatment Use: Questions and Answers

https://www.fda.gov/media/162793/download

2. Cross Labeling Oncology Drugs in Combination Regimens

https://www.fda.gov/media/162806/download

3. Assessing User Fees Under the Over-the-Counter Monograph Drug User Fee Program

https://www.fda.gov/media/162759/download\

4. Sameness Evaluations in an ANDA — Active Ingredients

https://www.fda.gov/media/163018/download

5. Referencing the Definition of “Device” in the Federal Food, Drug, and Cosmetic Act in Guidance, Regulatory Documents, Communications, and Other Public Documents

https://www.fda.gov/media/154866/download

6. Compounding Certain Beta-Lactam Products in Shortage Under Section 503A of the Federal Food Drug and Cosmetic Act

https://www.fda.gov/media/163367/download

7. Draft Guidance for Industry: Questions and Answers Regarding Food Allergen Labeling (Edition 5)

https://www.fda.gov/media/163454/download

8. Guidance for Industry: Questions and Answers Regarding Food Allergen Labeling (Edition 5)

https://www.fda.gov/media/117410/download

ICH:

9. S1B(R1) Addendum to S1B Testing for Carcinogenicity of Pharmaceuticals: Guidance for Industry

https://www.fda.gov/media/152777/download

10. M10 Bioanalytical Method Validation and Study Sample Analysis

https://www.fda.gov/media/162903/download

11. Q5A(R2) Viral Safety Evaluation of Biotechnology Products Derived From Cell Lines of Human or Animal Origin

https://www.fda.gov/media/163115/download

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